The insidious, invisible problem…
In NZ the average herd-level prevalence of subclinical hypocalcaemia is 52%**
The Calpro Bolus solution
Use Calpro Bolus for the prevention and treatment of subclinical hypocalcaemia and as an aid in the prevention and treatment of clinical hypocalcaemia (Milk Fever) in cows. Calpro Bolus offers peace of mind because it is the only ACVM registered calcium bolus and is supported by a published, peer-reviewed New Zealand study*.
A combination of academic and industry research is behind the design of Calpro Bolus, which dissolves within 50 minutes, rapidly delivering 43g of calcium to the rumen. Calcium is released in two forms, calcium chloride and calcium sulphate (refer to Fig 2.)
What is of critical importance with any supplementary calcium is that it does not interfere with the innate control mechanisms. Freshly calved cows need to access both the supplementary calcium and their own reserves.
Calpro Bolus boluses support the calcium control mechanism by lowering urine pH so natural body reserves of calcium are more readily available to the animal and assisting absorption of the supplementary calcium from the bolus within 1 hour of administration.
Chart adapted from Kimura K, Reinhardt TA, Goff JP. Parturition and hypocalcaemia blunts calcium signals in immune cells of dairy cattle. J Dairy Sci 2006;89:2588–95
*KI Roberts, J Bennison & S McDougall (2019) Effect of treatment with oral Ca boluses following calving on concentrations of Ca in serum in pasture-based dairy cows, New Zealand Veterinary Journal, 67:1, 20-26, DOI: 10.1080/00480169.2018.15206542
**KI Roberts & S McDougall (2019) Risk factors for subclinical hypocalcaemia, and associations between subclinical hypocalcaemia and reproductive performance, in pasture-based dairy herds in New Zealand, New Zealand Veterinary Journal, 67:1, 12-19, DOI: 10.1080/00480169.2018.1527732
***Goff JP. The monitoring, prevention and treatment of milk fever and subclinical hypocalcaemia in dairy cows. Vet J 2008;176(1):50–57